Platelet Rich Plasma Therapy

Platelet Rich Plasma Therapy

PRP in Mesa, Phoenix, Scottsdale, Gilbert, and Peoria

Desert Spine and Sports Physicians is the leading provider of non-surgical musculoskeletal therapies including the popular and proven regenerative therapy, Platelet Rich Plasma (PRP). We have been delivering PRP injections for over a decade, and it is our preferred regenerative treatment option for musculoskeletal injury because it is safe and effective. This therapy utilizes a concentrated form of platelets from a patient’s own blood, which have growth factors that accelerate the body’s natural healing process, leading to tissue repair and regeneration. PRP reduces pain and improves function in various musculoskeletal conditions, including joint, tendon, and ligament injuries.

How PRP Works


1. Joint Pain

PRP therapy can be used to alleviate joint pain, especially in conditions like osteoarthritis. Osteoarthritis is characterized by the breakdown of joint cartilage, leading to pain and reduced joint function. When PRP is injected into a joint, it is believed to:

  • Promote Healing: The growth factors in PRP can stimulate the production of new cartilage cells, which aids in repairing damaged cartilage and promoting tissue regeneration within the joint.
  • Reduce Inflammation: PRP’s anti-inflammatory properties can help to decrease the inflammation in the joint, which is often associated with pain and reduced mobility in conditions like arthritis.
  • Enhance Lubrication: PRP injections may improve the synovial fluid’s viscosity and lubricating properties within the joint, which alleviates pain, reduces friction, and enhances joint mobility.

2. Tendon and Ligament Pain

PRP therapy is also commonly used to treat tendon-related injuries, such as tendonitis or tendinosis/tendinopathy, and ligament injuries, such as sprains or strains. PRP therapy for tendon and ligament pain works by:

  • Enhancing Healing: The growth factors in PRP enhance collagen production, which heals injuries and promotes the growth of new, healthier tissue in damaged tendons and ligaments. This is particularly useful in chronic issues where healing is slow.
  • Reducing Pain: Just as in joint pain, the anti-inflammatory properties of PRP can reduce pain by reducing swelling and irritation in and around the affected tendon or ligament.
  • Strengthening Tissue: PRP stimulates the production of collagen, a key protein for tendon and ligament strength and function. Increased collagen production leads to improved tissue strength and stability and, therefore, reduced risk of re-injury.

How PRP is Made


1. Blood Collection

To create PRP, a small sample of the patient’s blood is taken, usually from a vein in the arm. The blood is then processed to separate its components.

2. Centrifugation

The collected blood is placed in a centrifuge, a machine that spins rapidly to separate different components of the blood based on their densities in a two-step process. This process separates the platelets with their growth factors from the other blood components, such as red blood cells and neutrophils.

3. Platelet-Rich Plasma

After centrifugation, the concentrated platelets, approximately 8x the amount of platelets as compared to whole blood, are separated from the rest of the blood. This concentrated solution is the Platelet-Rich Plasma.

4. Application

The PRP can then be injected into the site of injury or treatment. It is vital that PRP is injected with image guidance to ensure the therapy is delivered to the proper site.

It is important to note that while PRP therapy holds promise, its effectiveness can vary depending on factors such as the specific condition being treated, the severity of the condition, and the patient’s overall health. PRP therapy is generally considered safe because it utilizes the patient’s own blood components, reducing the risk of allergic or immune reactions. However, like any medical procedure, there can be potential risks and side effects, such as infection, pain at the injection site, or no significant improvement in symptoms.

If you are considering PRP therapy for your pain, it is essential to consult an expert in the field of musculoskeletal medicine who can assess your condition and determine whether PRP is a suitable option for you. Here at Desert Spine and Sports Physicians, our Physicians are fellowship-trained in Advanced Interventional Procedures, and together, we have garnered 38 “Top Doc” Phoenix Magazine awards. We have safely performed over 300,000 musculoskeletal injections and deliver all of our procedures accurately under image guidance such as ultrasound or fluoroscopy. If you are interested in knowing more about PRP therapy, we will schedule you for an initial visit billed to the insurance carrier (if contracted) to evaluate your issue and discuss how to prepare for the PRP injection. The PRP therapy, which is not covered by insurance and costs $900, will then be injected at the follow-up appointment.

At Desert Spine and Sports Physicians, we are constantly evaluating the best treatment options for our patients, and we are happy to discuss what really works when it comes to regenerative musculoskeletal medicine. We look forward to helping you manage your pain and injury and return you back to function. To book with us, please contact us at, or call us at 602-840-0681.

PRP References

– Tenforde, A., Robinson, D., Borg-Stein, J., Borgstrom, H. and Singh, J.R. (2020), Extracorporeal Shockwave Therapy Versus Platelet-rich Plasma for Achilles Tendinopathy. PM&R: The Journal of Injury, Function and Rehabilitation, 12: 1169-1176.


– Hasley IB, Bies MM, Hollman JH, Carta KG, Sellon JL, Brault JS. Platelet-Rich Plasma Injection for Thumb Carpometacarpal Joint Osteoarthritis. Arch Rehabil Res Clin Transl. 2023;5(1):100257. Published 2023 Jan 29. doi:10.1016/j.arrct.2023.100257


– Tang S, Wang X, Wu P, et al. Platelet-Rich Plasma Vs Autologous Blood Vs Corticosteroid Injections in the Treatment of Lateral Epicondylitis: A Systematic Review, Pairwise and Network Meta-Analysis of Randomized Controlled Trials. PM R. 2020;12(4):397-409. doi:10.1002/pmrj.12287


– Fitzpatrick J, Bulsara MK, O’Donnell J, Zheng MH. Leucocyte-Rich Platelet-Rich Plasma Treatment of Gluteus Medius and Minimus Tendinopathy: A Double-Blind Randomized Controlled Trial With 2-Year Follow-up. Am J Sports Med. 2019;47(5):1130-1137. doi:10.1177/0363546519826969


– Dallari D, Stagni C, Rani N, et al. Ultrasound-Guided Injection of Platelet-Rich Plasma and Hyaluronic Acid, Separately and in Combination, for Hip Osteoarthritis: A Randomized Controlled Study. Am J Sports Med. 2016;44(3):664-671. doi:10.1177/0363546515620383
– Lim A, Zhu JB, Khanduja V. The Use of Intra-articular Platelet-Rich Plasma as a Therapeutic Intervention for Hip Osteoarthritis: A Systematic Review and Meta-analysis [published online ahead of print, 2022 Jun 7]. Am J Sports Med. 2022;51(9):3635465221095563. doi:10.1177/03635465221095563
– Kraeutler MJ, Houck DA, Garabekyan T, Miller SL, Dragoo JL, Mei-Dan O. Comparing Intra-articular Injections of Leukocyte-Poor Platelet-Rich Plasma Versus Low-Molecular Weight Hyaluronic Acid for the Treatment of Symptomatic Osteoarthritis of the Hip: A Double-Blind, Randomized Pilot Study. Orthop J Sports Med. 2021;9(1):2325967120969210. Published 2021 Jan 20. doi:10.1177/2325967120969210


– Subramanyam K, Alguvelly R, Mundargi A, Khanchandani P. Single versus multi-dose intra-articular injection of platelet rich plasma in early stages of osteoarthritis of the knee: A single-blind, randomized, superiority trial. Arch Rheumatol. 2021;36(3):326-334. Published 2021 Jan 14. doi:10.46497/ArchRheumatol.2021.8408
– Filardo G, Previtali D, Napoli F, Candrian C, Zaffagnini S, Grassi A. PRP Injections for the Treatment of Knee Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials. Cartilage. 2021;13(1_suppl):364S-375S. doi:10.1177/1947603520931170
– Migliorini F, Driessen A, Quack V, et al. Comparison between intra-articular infiltrations of placebo, steroids, hyaluronic and PRP for knee osteoarthritis: a Bayesian network meta-analysis. Arch Orthop Trauma Surg. 2021;141(9):1473-1490. doi:10.1007/s00402-020-03551-y
– Han Y, Huang H, Pan J, et al. Meta-analysis Comparing Platelet-Rich Plasma vs Hyaluronic Acid Injection in Patients with Knee Osteoarthritis. Pain Med. 2019;20(7):1418-1429. doi:10.1093/pm/pnz011
– Kon E, Buda R, Filardo G, et al. Platelet-rich plasma: intra-articular knee injections produced favorable results on degenerative cartilage lesions. Knee Surg Sports Traumatol Arthrosc. 2010;18(4):472-479. doi:10.1007/s00167-009-0940-8
– Belk JW, Kraeutler MJ, Houck DA, Goodrich JA, Dragoo JL, McCarty EC. Platelet-Rich Plasma Versus Hyaluronic Acid for Knee Osteoarthritis: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Am J Sports Med. 2021;49(1):249-260. doi:10.1177/0363546520909397


Plantar Fascia
– Kalia RB, Singh V, Chowdhury N, Jain A, Singh SK, Das L. Role of Platelet Rich Plasma in Chronic Plantar Fasciitis: A Prospective Study. Indian J Orthop. 2020;55(Suppl 1):142-148. Published 2020 Oct 6. doi:10.1007/s43465-020-00261-w


– Nejati P, Ghahremaninia A, Naderi F, Gharibzadeh S, Mazaherinezhad A. Treatment of Subacromial Impingement Syndrome: Platelet-Rich Plasma or Exercise Therapy? A Randomized Controlled Trial. Orthop J Sports Med. 2017;5(5):2325967117702366. Published 2017 May 19. doi:10.1177/2325967117702366
– Prodromos CC, Finkle S, Prodromos A, Chen JL, Schwartz A, Wathen L. Treatment of Rotator Cuff Tears with platelet rich plasma: a prospective study with 2 year follow-up. BMC Musculoskelet Disord. 2021;22(1):499. Published 2021 May 29. doi:10.1186/s12891-021-04288-4


SI Joint
– Ling JF, Wininger AE, Hirase T. Platelet-Rich Plasma Versus Corticosteroid Injection for Lumbar Spondylosis and Sacroiliac Arthropathy: A Systematic Review of Comparative Studies. Cureus. 2021;13(3):e14062. Published 2021 Mar 23. doi:10.7759/cureus.14062

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